pentose phosphate pathway Mcqs
Which enzyme initiates the pentose phosphate pathway?
a. Glucose-6-phosphatase
b. Glucose-6-phosphate isomerase
c. Glucose-6-phosphate dehydrogenase
d. Hexokinase
Answer: c. Glucose-6-phosphate dehydrogenase
Which one is the primary product of the pentose phosphate
pathway?
a. Glucose-6-phosphate
b. Fructose-6-phosphate
c. Ribulose-5-phosphate
d. Phosphogluconate
Answer: c. Ribulose-5-phosphate
Which is the main
function of the pentose phosphate pathway?
a. ATP production
b. NADPH and pentose sugar production
c. Protein synthesis
d. Fatty acid synthesis
Answer: b. NADPH and pentose sugar production
What is the role of NADPH in the pentose phosphate pathway?
a. To provide energy for the reaction
b. To reduce glucose-6-phosphate to 6-phosphogluconolactone
c. To reduce NADP+ to NADPH
d. To convert 6-phosphogluconate to ribulose-5-phosphate
Answer: c. To reduce NADP+ to NADPH
Which of the following disorders is associated with a
deficiency in glucose-6-phosphate dehydrogenase?
a. Hemolytic anemia
b. Diabetes mellitus
c. Cystic fibrosis
d. Parkinson's disease
Answer: a. Hemolytic anemia
The pentose phosphate pathway is an alternative pathway to
which other pathway?
a. Glycolysis
b. TCA cycle
c. Oxidative phosphorylation
d. Lipid metabolism
Answer: a. Glycolysis
Which one enzyme is
responsible for the first step in the pentose phosphate pathway?
a. Glucose-6-phosphatase
b. Glucose-6-phosphate isomerase
c. Glucose-6-phosphate dehydrogenase
d. Hexokinase
Answer: c. Glucose-6-phosphate dehydrogenase
What is the primary function of NADPH generated in the
pentose phosphate pathway?
a. To provide energy for cellular processes
b. To synthesize ATP
c. To reduce glutathione and protect against oxidative
stress
d. To synthesize ribulose-5-phosphate
Answer: c. To reduce glutathione and protect against
oxidative stress
Which product of the pentose phosphate pathway is a
precursor for nucleotide biosynthesis?
a. Glucose-6-phosphate
b. Ribose-5-phosphate
c. 6-phosphogluconate
d. NADPH
Answer: b. Ribose-5-phosphate
What is the role of lactonase in the pentose phosphate
pathway?
a. To convert 6-phosphogluconate to ribulose-5-phosphate
b. To hydrolyze 6-phosphogluconolactone to
6-phosphogluconate
c. To produce NADPH from NADP+
d. To reduce ribulose-5-phosphate to glucose-6-phosphate
Answer: b. To hydrolyze 6-phosphogluconolactone to
6-phosphogluconate
Which of the following is a symptom of G6PD deficiency?
a. Anemia
b. Diabetes mellitus
c. Cystic fibrosis
d. Parkinson's disease
Answer: a. Anemia
Which of the following can regulate the activity of
glucose-6-phosphate dehydrogenase?
a. NADPH
b. NADP+
c. Glucose-6-phosphate
d. Both a and b
Answer: d. Both a and b
What is the last
product of the pentose phosphate pathway?
a. ATP
b. NADH
c. NADPH
d. Pyruvate
Answer: c. NADPH
Which of the following is an important function of NADPH?
a. ATP synthesis
b. DNA synthesis
c. Protein synthesis
d. Lipid degradation
Answer: b. DNA synthesis
Which of the following is a benefit of the pentose phosphate
pathway?
a. Production of ATP
b. Production of amino acids
c. Protection against oxidative stress
d. Breakdown of fatty acids
Answer: c. Protection against oxidative stress
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